This is one of the age old arguments. First of all a definition: vitamins are organic compounds needed in small amounts to ensure health. They cannot be naturally made in the body. Often deficiency in certain vitamins can lead to disease.
Vitamins are found naturally in organic compounds - the plants and meats we eat. Most doctors would say that you can get enough of your vitamins from eating whole foods. The problem is, most of us don't eat enough whole foods to deliver enough vitamins. So decades ago, vitamins began to be produced synthetically, i.e. in pill form. Through a chemical process, vitamins are distilled and extracted from organic compounds, including food sources or in some cases compounds like coal tar, to give us the vitamins you can buy on the shelf. A lot of the foods you eat contain added synthetic vitamins, from breads, to cereals, to clif bars, to health shakes (Shakeology does NOT have synthetic vitamins, more on that later). Since many synthetic vitamins are extracted from real foods and are chemcially identical to natural vitamins, they should interact exactly the same in our body. But some people disagree.
Read more: Natural Vs. Synthetic Vitamins